Research in my laboratory is focused to better understand how metabolic reprogramming regulates platelet and leukocyte function and whether targeting enzymes involved in aerobic glycolysis can inhibit thrombo-inflammation. If successful, this could be developed as a therapeutic strategy toward better management of patients at high risk for acute coronary events and stroke. We utilize state-of-the-art imaging techniques like intravital microscopy, laser-speckle imaging and magnetic resonance imaging in order to study mechanistic role of thrombo-inflammation in the modulation of acute ischemic stroke and thrombosis. In addition, research projects use molecular and cellular techniques, combined with genetically modified mice to investigate the role of novel molecules in the pathophysiology of atherosclerosis.
In addition, my laboratory is part of multi-center Stroke Preclinical Assessment Network (https://chauhan.lab.uiowa.edu/span) to test novel cerebroprotective drugs funded by NINDS.
Learn more about our research.
Recent News
Kumskova expands Ehlers-Danlos syndrome research with mentored grant (August 2024)
Ground-breaking science from postdoctoral fellows Rakeshkumar Patel, PhD, and Mariia Kumskova, MD, at the International Stroke Conference (February 2024)
Dr. Rakesh Patel receives AHA postdoctoral fellowship (December 2023)
Dr. Manasa Nayak receives Elaine W. Raines Early Career Investigator Award as a Finalist at Scientific Sessions 2023 (November, 2023)
NIH News: Researchers develop new method to identify potential stroke therapies (September, 2023)
Dr. Mariia Kumskova receives a 2023 ATVB Vascular Discovery Travel Grant for Early Career Investigators (April 2023)
Funding Sources
